Physique du Vivant
Présentation:
Dans l’équipe Physique du Vivant, nous étudions les mécanismes physiques qui sous-tendent les processus fondamentaux du vivant. Notre activité est surtout expérimentale mais comporte également un aspect modélisation. Nos recherches portent sur différents types d’organismes animaux et végétaux, dont nous caractérisons le comportement dans des contextes physiologiques et pathologiques (cancer, myopathies, maladie d’Alzheimer), avec des implications en santé environnementale. L’échelle de nos études s’étend du sub-cellulaire aux agrégats de cellules.
Actin network in plant protoplast in rectangular microwell (P. Durand)
Vesicules and silica nanoparticles (JF Berret)
MDCK epithelium (S. Hénon)
Stretched magnetic multicellular aggregate (M. Reffay)
À lire aussi
18-month post-doctoral fellowship on pulmonary surfactant
Structure and rheology of pulmonary surfactantResearch The INHALE project, funded by the French National Research Agency (ANR), seeks to investigate the viability of surfactant replacement therapy in adults afflicted with respiratory disorders. Pulmonary surfactant is...
18-month post-doctoral fellowship on lung function
On-chip model of mucociliary clearanceResearch The MucOnChip project, funded by the Agence Nationale de la Recherche (ANR), is dedicated to advancing our understanding of mucociliary clearance for the treatment of inflammatory lung diseases. Our primary goal is to...
Proposition de stage de M2/Thèse 2023-2024
Nuclear mechanics as a diagnostic and therapeutic target for glioblastoma Glioblastomas (GBMs) are the most lethal primary brain tumours. The absence of effective therapies is mainly due to tumour invasion and to the resistance of invading cells to treatments such as...
Postdoctoral position in cell biographysics – Mechanotransduction at the Golgi apparatus
A 2-year postdoctoral position starting in November 2023 is available in the ‘Physics of living systems’ team within the ‘Matter and complex systems’ (MSC) laboratory at Université Paris Cité, to study the mechanosensitive properties of the Golgi apparatus....
Stage M2/Thèse 2023-2024 : Mechanics and mechanosensitivity of mitochondria in living cells
Key words: metabolism; mitochondria; oxidative phosphorylation; ROS; optical tweezers; microfluidic;FRET; FLIM Collaborators: Catherine Villard (Institut Curie, Paris), Nicolas Borghi (Institut Jacques Monod, Paris),Tarik Issad, Clotilde Alves-Guerra et Renaud Dentin...